Although the size and grade of the DCIS can help predict if it will become invasive, there is currently no way of knowing if this will happen. High-grade DCIS is.
Ductal carcinoma in situ (DCIS) is a common pre-invasive malignancy of the breast, representing approximately 20% of all breast cancer diagnoses. Evidence shows that high-grade DCIS is an aggressive subtype with an overall poorer prognosis than non-high-grade disease.
Treatment based on grouping of DCIS tumors into low grade, high grade, After the biopsy, the pathologist analyzes the piece of breast tissue.